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Paclitaxel

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Updated on: 2021-11-10 15:26
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  Post Date: Nov 10,2021
  Expiry Date: May 09,2022
  Detailed Description: Cas No. :33069-62-4 Appearance White to pale yellow crystalline powder
Identification Infrared Absorption:In accordance with the reference Standard spectrum of paclitaxel
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation,as obtained in the Assay.
Specific Rotation -49.0°~-55.0°
RELATED COMPOUNDS
Baccatin III:≤0.2%
10-Deacetylpaclitaxel:≤ 0.5%
Photodegradant:≤0.2%
10-Debenzoylbaccatin III:≤0.1%
2-Debenzoylpaclitaxel-2-pentenoate :≤0.7%
10,13-Bissidechainpaclitaxel:≤0.5%
7-Acetylpaclitaxel:≤ 0.6%
7-Tes-paclitaxel:≤0.3%
13-Tes-baccatin III:≤ 0.1%
7-Epipaclitaxel:≤0.5%
Others:≤0.1% (each)
Total:≤ 2.0%
ORGANIC VOLATILE IMPURITIES Acetone:≤5000ppm
Hexane:≤290ppm
Water Content Not more than 4.0%
Residue On Ignition Not more than 0.2%
Heavy metals Not more than 0.002%
ASSAY (calculated on the anhydrous, solvent-free basis) 97.0%~102.0%

  CAS Registry Number:

33069-62-4

  Synonyms: ;7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.;taxal;taxol a;Taxol;
  Molecular Formula: C47H51NO14
  Molecular Weight: 853.9061
  Molecular Structure: 33069-62-4 Paclitaxelnload="javascript:DrawImage(this);">
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
R41:;
  Safety Description: S26:;
S36/37/39:;
S45:;

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